• En/中

    • Jinhui Li

    Bioinformatics algorithm and toolkit development

    Metagenomics/Assembly/Protein structure predict

    Basic information

    • Male / 27 Year-old
    • R/Python/PHP/MySQL/AI

    Contact

    IT Skill

    Wechat

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    Education

    • Saint Louis University - Bioinformatics（Ph.D）

      With the cooperation with Dr. Dapeng Zhang, I focus on the repeats on genomics.

    • Guangxi Iniversity - Bioengineer(Master)

      - My research focuses on the development of microbial informatics tools, biological databases, and the application of artificial intelligence prediction models in microbiology research.

      - Rankings 1/40, Published 2 English abstracts of international conferences, 5 publications（As first author in 2 paper） during the period. At the same time, got the Graduate National Scholarship, the Outstanding Students of Guangxi University and the Outstanding Graduates of Guangxi University.

    • Henan Normal University - Aquatic Science and Technology (Bachelor of Science in Agriculture)

      - Ranking 20/60，During my studies, I participated in research in the field of preparing marine drugs using complex coagulation method, and jointly published 3 papers.

    Work Experience

    • Sequencing Instrument R & D Center of BGI Group Co. , Ltd.

      • Position：Biological Information Assistant Researcher

      • Development and maintenance of a rapid identification and assembly traceability system for microorganisms, as well as maintenance of the bioinformatics workstation OS.

      • Development of tumor copy number variation detection tools.Calculate the number of copies of the deep relationship of the internal and target genes based on the standard of the standard sample.

      • DNA Multiple PCR Methylation Project

    • Jabrehoo 2011Peking Jabrehoo Med Tech Co.,Ltd

      • Postion：Biological information engineer
      • Participate in the data analysis, iteration of biological information processes, and partial development of cloud platforms for rare disease topics in embryo pre implantation genetic diagnosis and screening projects (PGS, PGD, PGT-A, PGT-M) in assisted reproduction, independently undertake and complete the development of sliding window testing and other functional points, maintain and repair auxiliary tools for analysis toolkits (GATK4, else) in carrier screening projects, etc.
      • Promote the cloud deployment of bioinformatics analysis processes, package process codes for remote single machine deployment.
      • Mainly responsible for the development of the bioinformatics process for DNA methylation projects,

    Project experience

    • [Project 1]Constructing a Microbiomics Prediction Model Based on Machine Learning
      Guangxi Innovation Project for graduate students

      • [Content] Based on the abundance of microbial species, a host trait prediction model was constructed using machine learning techniques Including random forest, support vector machine, and logistic regression.
        [Contribution] Research-design-implementation-paper writing-submission.
        [Effect]Completion（2022.4） Proj.：YCSW2021064.

    • [Project 2] Development of Multi omics Visualization Tools published

      • IT：HTML 5+D3.js+ECharts+MySQL+R+Python+Shiny
      • 访问：https://microbiosee.gxu.edu.cn
      • [Content]Realize data cleaning, analysis, and visualization display for microbial multi omics research
        [Contribution] Responsible for the overall structural design, development, debugging, article writing, and submission of the project. The graphical display of row data and the function of realizing online interactive visualization based on R and Python.
        [Effect] PublishedFrontiers in Genetics。

    • [Project 3] Development of sulfur circulating gene database Published

      • IT：HTML 5+D3.js+MySQL+R+Python
      • Visit：https://smdb.gxu.edu.cn/
      • [Content] Integrate genes and information related to sulfur metabolism from multiple databases to provide a professional database for sulfur metabolism research.
        [Contribution] Responsible for the design, development, and debugging of databases and websites. Built a MySQL database for data storage and web page access; In addition, combining scripts usingPHPandPythonprovides basic Blast functionality.
        [Effetc] Published。

    出版/著作

  • 1. Jinhui Li, Yimeng Sang, Sen Zeng, Shuming Mo, Zufan Zhang, Sheng He, Xinying Li, Guijiao Su, Jianping Liao, and Chengjian Jiang. MicrobioSee: a web-based visualization toolkit for multi-omics of microbiology. Frontiers in Genetics. 2022. 13: 853612. DOI: 10.3389/fgene.2022.853612.
  • 2. Mo, Shuming†, Jinhui Li†, Bin Li, Muhammad Kashif, Shiqing Nie, Jianping Liao, Guijiao Su, Qiong Jiang, Bing Yan, and Chengjian Jiang. 2021. "L-Cysteine Synthase Enhanced Sulfide Biotransformation in Subtropical Marine Mangrove Sediments as Revealed by Metagenomics Analysis" Water 13, no. 21: 3053. DOI:10.3390/w13213053
  • 3. Mo, Shuming, Sheng He, Yimeng Sang, Jinhui Li, Muhammad Kashif, Zufan Zhang, Guijiao Su, and Chengjian Jiang. "Integration of Microbial Transformation Mechanism of Polyphosphate Accumulation and Sulfur Cycle in Subtropical Marine Mangrove Ecosystems with Spartina alterniflora Invasion." Microbial Ecology (2022). DOI: 10.1007/s00248-022-01979-w.
  • 4. Zufan Zhang, Shiqing Nie, Yimeng Sang, Jinhui Li, et al. Effects of Spartina alterniflora invasion on nitrogen fixation and phosphorus solubilization in a subtropical marine mangrove ecosystem. Microbiology Spectrum. DOI: 10.1128/spectrum.00682-21.
  • 5. Nie, Shiqing, Zufan Zhang, Shuming Mo, Jinhui Li, Sheng He, Muhammad Kashif, Zhengwu Liang, Peihong Shen, Bing Yan, and Chengjian Jiang. "Desulfobacterales Stimulates Nitrate Reduction in the Mangrove Ecosystem of a Subtropical Gulf." Science of The Total Environment 769 (2021): 144562. DOI: 10.1016/j.scitotenv.2020.144562.
  • 7. Gao, Y. N, Dong, J., Fu, Q. Q., Wang, Y. P., Chen, C., & Li, J. H., et al. (2017) Allelopathic effects of submerged macrophytes on phytoplankton. Allelopathy Journal, 40(1), 1-22.